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May 13, - PDF | Cefuroxime levels were measured in cerebrospinal fluid (CSF) and serum of four patients with traumatic brain injury following the.

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Cephalosporins such as cefuroxime, cefixime and cefazolin have also been associated with High CSF penetration of the drug is cited as the likely cause of high rate of . T2 high signal lesions on brain MRI in the cerebellum and brainstem.

Aug 20, - These drugs have consistent cerebrospinal fluid (CSF) penetration and .. that can lead to cerebral herniation and irreversible brainstem injury.

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